产品名称

VA012

产品货号

Axon 2889 CAS [885898-58-8] MF C21H19N3MW 313.40 Purity: 99% Soluble in DMSO Recently added

产品价格

现货询价，电话：010-67529703

产品规格

产品品牌

axonmedchem

产品概述

产品详情

VA012

Based on 1 reference(s) in Google Scholar 8 10 1

Axon 2889

CAS [885898-58-8]

MF C21H19N3
MW 313.40

Purity: 99%
Soluble in DMSO

Recently added

VA012

Description

VA012 is a positive allosteric modulator of the serotonin 5-HT2C receptor with an EC50 value of 16 nM. VA012 exhibits enhanced efficacy dose-dependently, no significant off-target activities, and low competition with the endogenous agonist or other orthosteric ligands.

KEYWORDS: VA012 | supplier | PAM of 5-HT2C | VA 012 | VA-012 | CAS [885898-58-8] | Serotonin | 5-HT2C | PAM | Receptors | Obesity

J García-Cárceles et al. A Positive Allosteric Modulator of the Serotonin 5-HT2C Receptor for Obesity. J Med Chem. 2017 Dec 14;60(23):9575-9584.

CNS 5-HT2C A17

Positive allosteric modulator (PAM) of 5-HT2C receptor

Chemical name

N-((1-Benzyl-1H-indol-3-yl)methyl)pyridin-3-amine

Parent CAS No.

[885898-58-8]

产品资料