产品名称

ADX71743

产品货号

Axon 2732 CAS [N.A.] MF C17H19NO2MW 269.34 Purity: 99% Soluble in DMSO Description ADX71743 is a selective mGluR7 negative allosteric modulator. KEYWORDS: ADX71743 | supplier | mGLuR7 NAM | ADX71743 | ADX-71743 | ADX 71743 | Glutamate | mGluR7 | NAM | Receptors

产品价格

现货询价，电话：010-67529703

产品规格

产品品牌

axonmedchem

产品概述

产品详情

ADX71743

Based on 5 reference(s) in Google Scholar 8 10 5

Axon 2732

CAS [N.A.]

MF C17H19NO2
MW 269.34

Purity: 99%
Soluble in DMSO

ADX71743

Description

ADX71743 is a selective mGluR7 negative allosteric modulator.

KEYWORDS: ADX71743 | supplier | mGLuR7 NAM | ADX71743 | ADX-71743 | ADX 71743 | Glutamate | mGluR7 | NAM | Receptors

R Klar et al. Activation of Metabotropic Glutamate Receptor 7 Is Required for Induction of Long-Term Potentiation at SC-CA1 Synapses in the Hippocampus. J Neurosci. 2015 May 13;35(19):7600-15.

V Tassin et al. Phasic and Tonic mGlu7 Receptor Activity Modulates the Thalamocortical Network. Front Neural Circuits. 2016 Apr 25;10:31.

M Kalinichev et al. ADX71743, a potent and selective negative allosteric modulator of metabotropic glutamate receptor 7: in vitro and in vivo characterization. J Pharmacol Exp Ther. 2013 Mar;344(3):624-36.

CNS C3 mGluR7

Negative allosteric modulator (NAM) of mGluR7

Chemical name

6-(2,4-Dimethylphenyl)-2-ethyl-6,7-dihydrobenzo[d]oxazol-4(5H)-one

Parent CAS No.

[N.A.]

产品资料