Athens Research & Technology;16-16-090701;Immunoglobulin A (IgA), Human Plasma

型号:16-16-090701
联系人:程园
联系电话:18611717737
品牌:athens research & technology


Athens Research & Technology 公司位于美国乔治亚州雅典市,从1986年以来一直致力于纯化高纯度,高活性的人类蛋白质和开发这些蛋白的多克隆抗血清。我们的常规产品包括丝氨酸蛋白酶、蛋白酶抑制剂、中性粒细胞酶、载脂蛋白、脂蛋白,血小板蛋白、转铁蛋白、免疫球蛋白等。二十年多年来,世界各地的研究人员都在使用我们公司的产品。在炎症、冠状动脉疾病、自身免疫性疾病、癌症、老年痴呆症等等研究的主要科学出版物中都能看到引用我们公司的产品。
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MW 160,000
Extinction Coefficient = 1.32

Frozen in 100 mM Tris-HCl, pH 8.0, with 100 mM NaCl and 0.05% NaN3.


IgA is the most abundant immunoglobulin in body fluids and the second most abundant immunoglobulin in plasma, found at a concentration of 0.4 to 2.2 mg/ml. It plays a very important role in the first specific defense against natural infection. Secretory IgA differs from serum IgA in that it contains two additional peptides: the secretory component and the J chain.


Storage: <= -20°C

Purity: >=95% by SDS-PAGE

Prepared from plasma shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA-required tests.

Athens Research & Technology products are laboratory reagents and are not to be administered to humans or used for any drug purpose. For research or further manufacturing use only.


Product Citation:
Bidgood SR, et al. Translocalized IgA mediates neutralization and stimulates innate immunity inside infected cells. Proc Natl Acad Sci U S A. 2014 Sep 16;111(37):13463-8. doi: 10.1073/pnas.1410980111. Epub 2014 Aug 28.

Herati RS, et al. Circulating CXCR5+PD-1+ Response Predicts Influenza Vaccine Antibody Responses in Young Adults but not Elderly Adults. J Immunol. 2014 Oct 1;193(7):3528-37. doi: 10.4049/jimmunol.1302503. Epub 2014 Aug 29.


Ref: 
Mestecky, J. et al. 1971. J. Immunol. 107, 605; Mehl, V.S. and Penn, G.M. 1986. Manual of Clinical Laboratory Immunology (N.R. Rose, ed.), 126