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| Product Name | HDDC3, 1-140aa, Human, His tag, E Coli |
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| Description | MW: 17.9 kDa (160aa), confirmed by MALDI-TOF. Purity >90% by SDS-PAGE. HDDC3, also known as guanosine-3',5'-bis (diphosphate)-pyrophosphohydrolase MESH1, contains an active site for ppGpp hydrolysis and a conserved His-Asp-box motif for Mn (2+) binding. Consistent with these structural data, HDDC3 efficiently catalyzes hydrolysis of guanosine 3',5'-diphosphate (ppGpp) both in vitro and in vivo. HDDC3 also suppresses SpoT-deficient lethality and RelA-induced delayed cell growth in bacteria. Recom |
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| Size | 0.1 mg, 0.5 mg |
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| Concentration | 0.5 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [Guanosine-3'5'-bis (diphosphate)-pyrophosphohydrolase MESH1; Guanosine-3',5'-bis (diphosphate)-pyrophosphohydrolase MESH1; MESH1; ppGpp] |
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| Gene, Accession, CAS # | HDDC3, Gene ID: 374659, Accession: NP_940929 |
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| Catalog # | MBS204110 |
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| Order / More Info | HDDC3, 1-140aa, Human, His tag, E Coli from MYBIOSOURCE INC. |
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| Product Specific References | Sun D., et al. (2010) Nat. Struct. Mol. Biol. 17:1188-1194; Zody M.C., et al. (2006) Nature. 440:671-675 |
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