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| Product Name | Recombinant Human PDGF-B Protein |
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| Description | Purity >95% as determined by SDS-PAGE. Platelet-derived growth factor (PDGF) is an important regulator of cell growth, proliferation, and angiogenesis. PDGF synthesis is induced by IL-1, IL-6, TNF-a, TGF-b and EGF signaling. PDGF functions as a mitogenic growth hormone on cells of mesenchymal lineage, such as smooth muscle and glial cells. PDGF is also stored in the alpha-granules of platelets and is released upon adherence to traumatized tissues. PDGF is a dimeric glycoprotein formed by two A chains (AA), two B chains (BB), or as a heterodimer with an A and a B chain (AB). The PDGF dimer binds the cell surface receptor tyrosine kinases PDGFR-a and PDGFR-b. |
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| Size | 10ug, 100ug, 1mg |
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| Concentration | n/a |
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| Applications | Bioactive |
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| Other Names | PDGF-B, IBGC5, PDGF2, SSV, PDGF-2, SIS, c-sis |
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| Gene, Accession, CAS # | PDGFB, Gene ID: 5155, UniProt: P01127 |
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| Catalog # | QP5307-10ug |
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| Order / More Info | Recombinant Human PDGF-B Protein from ENQUIRE BIOREAGENTS |
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| Product Specific References | n/a |
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