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| Product Name | SAE1, 1-346aa, Human, His-T7 tag, E Coli |
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| Description | MW: 42.2 kDa (378aa) confirmed by MALDI-TOF. Purity >90% by SDS-PAGE. SAE1, also known as AOS1, belongs to the ubiquitin-activating E1 family of proteins and plays an important role in the first step of the uBL1 conjugation pathway. Proteins conjugated to ub are marked for progressive degradation by the 26S Proteasome. SAE1, which is a dimeric enzyme, functions as a uBLI E1 ligase mediating the ATP-dependent activation of uBL1. This protein can bind with uBLE1A and uBLE1B to form a heterodimer w |
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| Size | 0.05 mg, 0.25 mg |
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| Concentration | 1 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [SuMO1 activating enzyme subunit 1; AOS1; HSPC140; SuA1; uBLE1A; SuMO1 activating enzyme subunit 1; ubiquitin-like 1-activating enzyme E1A; AOS 1; HSPC 140; SuA 1; uBLE 1A; uBL E1A; SAE 1; ubiquitin like protein SuMO 1 activating enzyme] |
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| Gene, Accession, CAS # | SAE1, Gene ID: 10055, Accession: NP_005491 |
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| Catalog # | MBS203729 |
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| Order / More Info | SAE1, 1-346aa, Human, His-T7 tag, E Coli from MYBIOSOURCE INC. |
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| Product Specific References | Boggio R., et al. (2007) J Biol Chem. 282 (21):15376-82.; Jones MC., et al. (2006) Proc Natl Acad Sci u S A. 103 (44):16272-7.; |
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