| 产品详情 |
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| Product Name | IPA-3 |
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| Description | A cell-permeable allosteric inhibitor of PAK1 that is non-competitive with respect to ATP binding (IC50 = 2.5 µM); binds covalently to the PAK1 regulatory domain (apparent Kd = 1.9 uM) and prevents binding to the upstream activator Cdc42 |
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| Size | 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 1081767-20-5 Pak-1 Pak1 cancers inhibitors signals transduction autoinhibitory kinases allosteric domains PAK1 PAKs 1 one inhibits inhibition P21-activated P21 P-21 P 21 activated IPA3 IPAs 3 three IPA-3 ATP binding binds adenosine 5-triphosphates non-competitive noncompetitive non competitive cdc42 cdc-42 cdcs 42 upstream up-stream up stream serine threonine cells functions blocks activity human upregulated |
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| Gene, Accession, CAS # | CAS: 42521-82-4 |
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| Catalog # | 14759-25 |
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| Price | |
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| Order / More Info | IPA-3 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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