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Product Name | IPA-3 |
Description | IPA-3 is a cell-permeable allosteric inhibitor of PAK1 (tha p21-activated kinase 1) that is non-competitive with respect to ATP binding (IC50 = 2.5 µM). It does not, however, inhibit the activity of PAK1 that has been pre-activated with Cdc42. IPA-3 binds covalently to the PAK1 regulatory domain (apparent Kd = 1.9 uM) and prevents binding to the upstream activator Cdc42. Potential anti-tumor agent. MW: 350.45. Purity ≥95% |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 1,?1'-?dithiobis-?2-?naphthalenol |
Gene, Accession, CAS # | CAS: 42521-82-4 |
Catalog # | 2647-5 |
Price | |
Order / More Info | IPA-3 from BIOVISION, INC. |
Product Specific References | n/a |
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