| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | beta Catenin |
|---|
| Clone | E247 |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | human, mouse |
|---|
| Isotype | IgG |
|---|
| Format | purified |
|---|
| Size | 1 mL |
|---|
| Concentration | n/a |
|---|
| Applications | Immunocytochemistry: 1:250, Immunofluorescence: 1:250, Immunohistochemistry (Paraffin): 1:125, Western Blot: 1:500 |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | beta Catenin Monoclonal Antibody (E247). Beta-catenin, an adherens junction (AJ) protein, was originally identified as a component of cell-cell adhesion structures. AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. Beta-catenin interacts with the cytoplasmic domain of E-cadherin and links E-cadherin to alpha-catenin, which in turn mediates anchorage of the E-cadherin complex to the cortical actin cytoskeleton. Studies show that Beta-catenin also binds to another cytoskeletal complex containing the adenomatous polyposis coli protein and microtubules, and interacts with several signaling pathways that include tyrosine kinases, phosphatases and Wnt/Wingless. The i |
|---|
| Immunogen | n/a |
|---|
| Other Names | catenin beta-1 |
|---|
| Gene, Accession # | Entrez: 12387, 1499; Uniprot: P35222, Q02248 |
|---|
| Catalog # | MA5-14461 |
|---|
| Price | |
|---|
| Order / More Info | beta Catenin Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | PubMed: 21883740, 25826270, 27260518 |
|---|
| 产品资料 |
|
|