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| Product Name | PYR 41 |
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| Description | Cell-permeable, irreversible ubiquitin-activating enzyme (E1) inhibitor (IC50 < 10 μM). Blocks ubiquitination and prevents ubiquitin-mediated proteasomal degradation. Inhibits NF-κB activation, blocks degradation of p53, increases p21 levels and induces apoptosis in vitro. Also causes an increase in sumoylation of proteins. Purity 98%. MW (observed): 371.3 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 4-[4-[(5-Nitro-2-furanyl)methylene]-3,5-dioxo-1-pyrazolidinyl]benzoic acid ethyl ester |
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| Gene, Accession, CAS # | CAS: 418805-02-4 |
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| Catalog # | 2978/10 |
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| Price | |
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| Order / More Info | PYR 41 from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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