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| Product Name | Recombinant Avian infectious bursal disease virus Structural polyprotein, partial |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 36.8kDa. Partial: 723-1012aa. N-terminal 6xHis-tagged. Avian infectious bursal disease virus (strain Cu-1) (IBDV) (Gumboro disease virus). Capsid protein VP2 self assbles to form an icosahedral capsid with a T=13 symmetry, about 70 nm in diameter, and consisting of 260 VP2 trimers. The capsid encapsulates the genomic dsRNA. VP2 is also involved in attachment and entry into the host cell by interacting with host ITGA4/ITGB1.The precursor of VP2 plays an important role in capsid assbly. First, pre-VP2 and VP2 oligomers assble to form a procapsid. Then, the pre-VP2 intermediates may be processed into VP2 proteins by proteolytic cleavage mediated by VP4 to obtain the mature virion. The final capsid is composed of pentamers and hexamers but VP2 has a natural tendency to assble into all-pentameric structures. Therefore pre-VP2 may be required to allow formation of the hexameric structures.Protease VP4 is a serine protease that cleaves the polyprotein into its final products. Pre-VP2 is first partially cleaved, and may be completely processed by VP4 upon capsid maturation. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | n/a |
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| Gene, Accession, CAS # | UniProt: P15480 |
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| Catalog # | RPC24444 |
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| Order / More Info | Recombinant Avian infectious bursal disease virus Structural polyprotein, partial from BIOMATIK |
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| Product Specific References | n/a |
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