| 产品详情 |
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| Antigenic Specificity | EHMT1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 100 ul |
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| Concentration | n/a |
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| Applications | WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit polyclonal to EHMT1.EHMT1 is a Histone-lysine N-methyltransferase that specifically mono-and dimethylates 'Lys-9' ofhistone H3 (H3K9me1 and H3K9me2, respectively) in euchromatin. H3K9me represents a specific tagfor epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones. EHMT1also weakly methylates 'Lys-27' of histone H3 (H3K27me). EHMTa is also required for DNAmethylation independent of its histone methyltransferase. During G0 phase, EHMT1 contributes tosilencing of MYC-and E2F-responsive genes, suggesting a role in G0/G1 transition in cell cycle. Inaddition to the histone methyltransferase activity, EHMT1 also methylates non-histone proteins, suchas the dimethylation of 'Lys-373' of p53/TP53. |
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| Immunogen | C-terminal region of human EHMT1 |
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| Other Names | EHMT1,Histonelysine Nmethyltransferase,Euchromatic histonelysine Nmethyltransferase 1,G9alikeprotein 1,Histone H3K9 methyltransferase 5,H3K9HMTase 5,Lysine Nmethyltransferase 1D,EUHMTASE1,GLP,KIAA1876,KMT1D |
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| Gene, Accession # | UniProt: Q9H9B1 |
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| Catalog # | orb66842 |
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| Price | |
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| Order / More Info | EHMT1 Antibody from BIORBYT LTD. |
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| Product Specific References | n/a |
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