| 产品详情 |
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| Antigenic Specificity | Nod2 |
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| Clone | 26mNOD2 |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG1, kappa |
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| Format | purified |
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| Size | 50 µg |
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| Concentration | n/a |
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| Applications | Western Blot: Assay-Dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Nod2 Monoclonal Antibody (26mNOD2), eBioscience™. NOD2 is a member of the apoptosis regulating protein family that includes caspase recruitment-domains, as well as Apaf-1 and NOD1. It contains two N-terminal CARDs, a nucleotide binding domain (NBD), and multiple C-terminal leucine-rich repeats (LRRs). NOD2 is expressed in monocytes (whereas NOD1 is expressed in multiple tissues). NOD2 plays a role in regulating NF-kappaB, acts as an intracellular receptor for bacterial lipopolysaccharides, and contributes to inflammatory bowel disease (IBD) and Crohn's disease. |
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| Immunogen | n/a |
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| Other Names | NOD-2, NOD 2, CARD15, Caspase recruitment domain protein 15, IBD1, Inflammatory Bowel disease protein 1 |
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| Gene, Accession # | Entrez: 257632; Uniprot: Q8K3Z0 |
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| Catalog # | 14-5858-81 |
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| Price | |
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| Order / More Info | Nod2 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 24324812, 25429073, 27492130, 28029143 |
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