| 产品详情 |
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| Antigenic Specificity | NOD2 |
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| Clone | 2D9 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: Assay-Dependent, Immunofluorescence: Assay-Dependent, Immunohistochemistry (Paraffin): 1:10-1:500, Immunoprecipitation: 1:10-1:500, Western Blot: 1:100-1:2000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | NOD2 Monoclonal Antibody (2D9). NOD2 is a member of the apoptosis regulating protein family that includes caspase recruitment-domains, as well as Apaf-1 and NOD1. It contains two N-terminal CARDs, a nucleotide binding domain (NBD), and multiple C-terminal leucine-rich repeats (LRRs). NOD2 is expressed in monocytes (whereas NOD1 is expressed in multiple tissues). NOD2 plays a role in regulating NF-kappaB, acts as an intracellular receptor for bacterial lipopolysaccharides, and contributes to inflammatory bowel disease (IBD) and Crohn's disease. |
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| Immunogen | n/a |
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| Other Names | NOD-2, NOD 2, CARD15, Caspase recruitment domain protein 15, IBD1, Inflammatory Bowel disease protein 1 |
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| Gene, Accession # | Entrez: 257632, 64127; Uniprot: Q8K3Z0, Q9HC29 |
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| Catalog # | MA1-16611 |
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| Price | |
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| Order / More Info | NOD2 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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