| 产品详情 |
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| Antigenic Specificity | NOD3 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 20 µg/mL, Immunofluorescence: 20 µg/mL, Western Blot: 1-2 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | NOD3 Polyclonal Antibody. NOD3 is a member of the NOD (nucleotide-binding oligomerization domain) family, a group of proteins that are involved in innate immune defense. NOD3 also known as NLR family CARD containing 3 (NLRC3), is predominantly expressed in the immune system, particularly in T lymphocytes, and its expression is strongly down-regulated following stimulation of the T-cell receptor complex and CD28, suggesting that NOD3 plays a role in attenuating the activation of T cells. NOD3 inhibits NF-βB, AP-1 and NFAT transcriptional activation in Jurkat T cells downstream of CD3/CD28 stimulation or treatment with PMA/ionomycin and decreases IL-2 and CD25 mRNA induction in activated cells. |
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| Immunogen | n/a |
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| Other Names | CLR16.2, NOD3; CARD15-like protein; NOD-like receptor C3; caterpiller 16.2; caterpiller protein 16.2; nucleotide-binding oligomerization domain protein 3; nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 3; protein NLRC3 |
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| Gene, Accession # | Entrez: 197358, 268857, 287070; Uniprot: Q5DU56, Q7RTR2 |
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| Catalog # | PA5-21016 |
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| Price | |
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| Order / More Info | NOD3 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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