产品详情 |
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Antigenic Specificity | CD152 (CTLA-4) |
Clone | UC10-4B9 |
Host Species | Armenian Hamster |
Reactive Species | mouse |
Isotype | IgG |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Flow Cytometry: 0.5 µg/test, Immunoprecipitation: Assay-Dependent |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD152 (CTLA-4) Monoclonal Antibody (UC10-4B9), eBioscience™. CTLA4 (Cytotoxic T-Lymphocyte Antigen 4) is a CD28-family receptor expressed on mainly CD4+ T cells. It binds the same ligands as CD28 (CD80 and CD86 on B cells and dendritic cells), but with higher affinity than CD28. However, in contrast to CD28 which enhances cell function when bound at the same time as the T cell receptor, CTLA4 inhbits the T cell and prevents it from functioning. Intracellular CTLA4 is also found in regulatory T cells and may be important to their function. |
Immunogen | n/a |
Other Names | CELIAC3, CTLA-4, GRD4, GSE, ICOS, IDDM12, CD152 isoform, celiac disease 3, cytotoxic T lymphocyte associated antigen 4 short spliced form, cytotoxic T-lymphocyte antigen 4 |
Gene, Accession # | Entrez: 12477; Uniprot: P09793 |
Catalog # | 14-1522-82 |
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Order / More Info | CD152 (CTLA-4) Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 17488719, 19066315, 19412181, 21266779, 21347344, 21498664, 21629267, 22105735, 22711708, 22750193, 23226238, 23817420, 23933188, 24903657, 24945807, 24979767, 25821220, 26107883, 26157175, 27479084, 27498556, 27588200, 28031335, 28049829, 28194010, 28393916, 28402334, 29352742 |
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