| 产品详情 |
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| Antigenic Specificity | CD80 (B7-1) |
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| Clone | 1G10 |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG2a |
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| Format | PE-Cyanine5 conjugate |
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| Size | 1 mL |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 0.2 µg/10^6 cells |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD80 (B7-1) Monoclonal Antibody (1G10), PE-Cyanine5. CD80 (B7-1) is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is constitutively expressed by dendritic cells, monocytes, and peritoneal macrophages. Expression of CD80 on B cells is upregulated after activation by various means including stimulation by LPS, IL-4, and surface Ig receptor crosslinking with peak expression occurring between 48 and 72 hours post-activation. The interaction of CD80 with its ligands, CD28 and CD152 (CTLA-4), provides a potent costimulatory signal for T cells activated through the CD3/T cell receptor complex. The monoclonal antibody 1G10 blocks binding of CTLA-4 to CD80 but it does not block stimu |
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| Immunogen | n/a |
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| Other Names | B7-1, Ly-53 |
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| Gene, Accession # | Entrez: 12519; Uniprot: Q00609 |
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| Catalog # | MA5-28657 |
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| Price | |
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| Order / More Info | CD80 (B7-1) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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