| 产品详情 |
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| Antigenic Specificity | CD80 (B7-1) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | lyophilized |
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| Applications | Western Blot: 0.5 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD80 (B7-1) Polyclonal Antibody. Cluster of Differentiation 80 (also CD80 and B7-1) is a protein found on activated B cells and monocytes that provides a costimulatory signal necessary for T cell activation and survival. It is the ligand for two different proteins on the T cell surface: CD28 (for autoregulation and intercellular association) and CTLA-4 (for attenuation of regulation and cellular disassociation). CD80 works in tandem with CD86 to prime T cells. The CD80 genes encode B7-1 which are structurally similar members of the immunoglobulin superfamily expressed on a variety of hematopoietic cell types. Reeves et al. (1997) stated that B7-1 and B7-2 provide a costimulatory signal to T cells by interacting with CD28 and CTLA4. |
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| Immunogen | n/a |
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| Other Names | CD80 antigen, isoform CRA_a |
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| Gene, Accession # | Entrez: 25408 |
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| Catalog # | PA5-79002 |
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| Order / More Info | CD80 (B7-1) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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