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| Product Name | IDO1, 1-403aa, Human, His-tag, E.coli (Bioactivity Validated) |
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| Description | Purity: > 90% by SDS - PAGE Format: Liquid. In 20mM Tris-HCl buffer (pH8.0) containing 0.15M NaCl, 20% glycerol, 1mM DTT. IDO1 is an indoleamine 2,3-dioxygenase - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, and serotonin. It is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan. Recombinant human IDO1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
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| Size | 100ug, 20ug, 4ug |
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| Concentration | n/a |
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| Applications | Enzyme activity |
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| Other Names | Indoleamine 2,3-dioxygenase 1, IDO, IDO-1, INDO |
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| Gene, Accession, CAS # | NP 002155 |
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| Catalog # | ATGP3488 |
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| Order / More Info | IDO1, 1-403aa, Human, His-tag, E.coli (Bioactivity Validated) from ATGen |
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| Product Specific References | n/a |
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