| 产品详情 |
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| Antigenic Specificity | CD86 |
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| Clone | GL-1 |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG2a |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 2 µg/mL, Functional Assay: Assay Dependent, Immunocytochemistry: Assay Dependent, Immunohistochemistry (Frozen): Assay Dependent, Immunoprecipitation: Assay Dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD86 Monoclonal Antibody (GL-1). CD86 is one of two ligands (the other CD80) for CTLA4 and CD28. CD86 acts as costimulatory molecule in eliciting T-cell help during antigen presentation. Antigen presentation in the absence of sufficient co-stimulation involving CD86/CD80 can induce tolerance. CD80 appears to play a role distinct from CD80 in T helper cell differentiation. CD86 is a type I membrane protein that is a member of the immunoglobulin superfamily. The CD86 protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of CD86 with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding |
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| Immunogen | n/a |
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| Other Names | B7-2, B7.2, B70, CD28LG2, LAB72, MGC34413, B-lymphocyte activation antigen B7-2, B-lymphocyte antigen B7-2, B7-2 antigen, BU63, CD28 antigen ligand 2 |
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| Gene, Accession # | Entrez: 12524; Uniprot: P42082 |
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| Catalog # | MA1-10299 |
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| Price | |
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| Order / More Info | CD86 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 10891477, 27471636, 27874077, 28069953, 28143686, 28290538 |
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