| 产品详情 |
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| Product Name | BABAM1, 1-329aa, Human, His tag, E.coli |
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| Description | Purity: > 85% by SDS - PAGE Format: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol, 0.1M NaCl. BABAM1 is a component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). The BRCA1-A complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX. In the BRCA1-A complex, it is required for the complex integrity and its localization at DSBs. Recombinant human BABAM1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. |
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| Size | 0.5mg, 100ug, 20ug |
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| Concentration | n/a |
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| Applications | SDS-PAGE |
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| Other Names | BRISC and BRCA1-A complex member 1, C19orf62, HSPC142, MERIT40, NBA1 |
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| Gene, Accession, CAS # | NP 001028721 |
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| Catalog # | ATGP2780 |
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| Order / More Info | BABAM1, 1-329aa, Human, His tag, E.coli from ATGen |
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| Product Specific References | n/a |
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