| 产品详情 |
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| Antigenic Specificity | IL-17A |
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| Clone | eBio17CK15A5 |
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| Host Species | Rat |
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| Reactive Species | mouse, rat |
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| Isotype | IgG2a, kappa |
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| Format | purified |
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| Size | 50 µg |
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| Concentration | n/a |
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| Applications | ELISA: 1-4 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | IL-17A Monoclonal Antibody (eBio17CK15A5), eBioscience™. Interleukin-17A (IL-17A, CTLA-8) is a CD4+ T cell-derived cytokine that promotes inflammatory responses in cell lines and is elevated in rheumatoid arthritis, asthma, multiple sclerosis, psoriasis, and transplant rejection. IL-17A is a 32 kDa long, disulfide-linked homodimer consisting of 136 amino acids that is a member of a six-species family of proteins (IL-17A-17F) and signals through the IL-17 receptor (IL-17R/CDw217). High levels of IL-17A homodimer are produced by activated peripheral blood CD4+ T-cells, and IL-17A also enhances expression of the intracellular adhesion molecule-1 (ICAM-1) in human fibroblasts. In particular, human IL-17A also stimulates epithelial, endoth |
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| Immunogen | n/a |
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| Other Names | Interleukin-17 |
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| Gene, Accession # | Entrez: 16171, 301289; Uniprot: Q61453, Q62386 |
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| Catalog # | 14-7175-81 |
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| Price | |
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| Order / More Info | IL-17A Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 21209700, 23686493, 23817416, 23878307, 24919069, 25630305, 27402698, 27779193, 28087667 |
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