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Antigenic Specificity | IL-17A |
Clone | eBio64CAP17 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, kappa |
Format | purified |
Size | 500 µg |
Concentration | n/a |
Applications | ELISA: 0.5-2 µg/mL, Flow Cytometry: Assay-Dependent, Immunohistochemistry (Frozen): Assay-Dependent, Immunoprecipitation: Assay-Dependent |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | IL-17A Monoclonal Antibody (eBio64CAP17), eBioscience™. Interleukin-17A (IL-17A, CTLA-8) is a CD4+ T cell-derived cytokine that promotes inflammatory responses in cell lines and is elevated in rheumatoid arthritis, asthma, multiple sclerosis, psoriasis, and transplant rejection. IL-17A is a 32 kDa long, disulfide-linked homodimer consisting of 136 amino acids that is a member of a six-species family of proteins (IL-17A-17F) and signals through the IL-17 receptor (IL-17R/CDw217). High levels of IL-17A homodimer are produced by activated peripheral blood CD4+ T-cells, and IL-17A also enhances expression of the intracellular adhesion molecule-1 (ICAM-1) in human fibroblasts. In particular, human IL-17A also stimulates epithelial, endothe |
Immunogen | n/a |
Other Names | Interleukin-17 |
Gene, Accession # | Entrez: 3605; Uniprot: Q16552 |
Catalog # | 14-7178-85 |
Price | |
Order / More Info | IL-17A Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 17652082, 18941119, 19729671, 20554959, 21082024, 21677143, 21876747, 21921207, 21926348, 22048775, 22669579, 22805180, 23382115, 23401593, 23518597, 23683514, 23823618, 24270423, 24866539, 25894502, 26339310, 27082311, 27246196, 27271570, 27777982, 28886145 |
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