产品详情 |
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Antigenic Specificity | IL-17A |
Clone | eBio64DEC17 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, kappa |
Format | purified |
Size | 25 µg |
Concentration | n/a |
Applications | ELISA: Assay-Dependent, Immunohistochemistry (Frozen): Assay-Dependent |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | IL-17A Monoclonal Antibody (eBio64DEC17), eBioscience™. Interleukin-17A (IL-17A, CTLA-8) is a CD4+ T cell-derived cytokine that promotes inflammatory responses in cell lines and is elevated in rheumatoid arthritis, asthma, multiple sclerosis, psoriasis, and transplant rejection. IL-17A is a 32 kDa long, disulfide-linked homodimer consisting of 136 amino acids that is a member of a six-species family of proteins (IL-17A-17F) and signals through the IL-17 receptor (IL-17R/CDw217). High levels of IL-17A homodimer are produced by activated peripheral blood CD4+ T-cells, and IL-17A also enhances expression of the intracellular adhesion molecule-1 (ICAM-1) in human fibroblasts. In particular, human IL-17A also stimulates epithelial, endothe |
Immunogen | n/a |
Other Names | Interleukin-17 |
Gene, Accession # | Entrez: 3605; Uniprot: Q16552 |
Catalog # | 14-7179-80 |
Price | |
Order / More Info | IL-17A Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 18433499, 19229322, 19386801, 20029330, 20833836, 20889558, 21147109, 21148794, 21384333, 21715501, 22058139, 22442208, 22485125, 22795370, 23719298, 23838472, 24120361, 24150258, 24788601, 24808367, 24879794, 25329329, 25339666, 25803478, 26321145, 26339310, 26375594, 26795030, 26995719, 27246196, 27338729, 27606804, 27898732, 27917174, 27922688, 28388924, 28768912, 29150604 |
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