| 产品详情 |
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| Product Name | Latanoprost ethyl amide |
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| Description | Latanoprost ethyl amide (Lat-NEt) is a latanoprost analog in which the C-1 carboxyl group has been modified to an N-ethyl amide. Prostaglandin esters have been shown to have ocular hypotensive activity.{8837} Prostaglandin N-ethyl amides were recently introduced as alternative prostaglandin ocular hypotensive prodrugs.{8941} Although it has been claimed that prostaglandin ethyl amides are not converted to the free acids in vivo,{8641} studies in our laboratories have shown that bovine and human corneal tissue converts the N-ethyl amides of various prostaglandins to the free acids with a conversion rate of about 2.5 µg/g corneal tissue/hr.{9311} Lat-NEt would be expected to show the typical intraocular effects of Latanoprost free acid, but with the much slower hydrolysis pharmacokinetics of the prostaglandin N-amides. |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Lat-NEt |
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| Gene, Accession, CAS # | CAS: 607351-44-0 |
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| Catalog # | 16822-5 |
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| Order / More Info | Latanoprost ethyl amide from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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