| 产品详情 |
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| Antigenic Specificity | eIF2 alpha subunit 1 Ser52 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | Protein A purified |
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| Size | 100ul |
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| Concentration | 1ug/ul |
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| Applications | WB, IHC-P, IF(IHC-P) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | eIF2 alpha subunit 1 (Ser52) Antibody. • Target Background: Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 4S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 6S ribosomal subunit to form the 8S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP |
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| Immunogen | KLH conjugated synthetic phosphopeptide derived from human eIF2 alpha subunit 1 around the phosphorylation site of Ser52 [EL(p-S)RR]. Immunogen Range: 50-91/315 |
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| Other Names | Phosphorylated, phospho-EIF2; EIF-2; EIF2A; EIF-2A; EIF-2alpha; Eukaryotic translation initiation factor 2 subunit 1; Eukaryotic translation initiation factor 2 subunit alpha; eIF-2-alpha; EIF2S1 |
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| Gene, Accession # | Gene ID: 1965, SwissProt: P05198 |
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| Catalog # | bs-4842R |
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| Price | |
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| Order / More Info | eIF2 alpha subunit 1 Ser52 Antibody from BIOSS ANTIBODIES |
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| Product Specific References | He, Yihuai, et al. (2014) Mol Cell Biochem. 389(1-2):151-8. PubMed: 24390087 // Yao et al. (2017) Nat.Commu. 8:133. PubMed: 28743963 // Li, et al. (2018) Toxicology Letters. 285:156-167. PubMed: 29306025 |
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