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| Product Name | NEuRL2, 1-285aa, Human, His tag, E.coli (Denatured) |
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| Description | Purity: > 85% by SDS - PAGE Format: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.4M uREA, 10% glycerol. NEuRL2 plays an important role in the process of myofiber differentiation and maturation. This protein is probable substrate-recognition component of a SCF-like ECS (Elongin BC-CuL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex, which mediates the ubiquitination of proteins. It probably contributes to catalysis through recognition and positioning of the substrate and the ubiquitin-conjugating enzyme. During myogenesis, NEuRL2 controls the ubiquitination and degradation of the specific pool of CTNNB1/beta-catenin located at the sarcolemma. Recombinant human NEuRL2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
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| Size | 250ug, 50ug, 10ug |
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| Concentration | n/a |
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| Applications | SDS-PAGE |
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| Other Names | neuralized homolog 2, C20orf163, OZZ, Ozz-E3 |
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| Gene, Accession, CAS # | NP 542787 |
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| Catalog # | ATGP2297 |
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| Order / More Info | NEuRL2, 1-285aa, Human, His tag, E.coli (Denatured) from ATGen |
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| Product Specific References | n/a |
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