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| Product Name | CFB, 26-259aa, Human, His-tag, Baculovirus |
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| Description | Purity: > 95% by SDS - PAGE Format: Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol.. CFB, also known as complement factor B, is a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation. Recombinant human CFB protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
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| Size | 250ug, 50ug, 10ug |
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| Concentration | n/a |
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| Applications | SDS-PAGE |
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| Other Names | Complement factor B, CFB, AHUS4, ARMD14, BF, BFD, CFAB, CFBD, FB, FBI12, GBG, H2-Bf, PBF2 |
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| Gene, Accession, CAS # | NP 001701 |
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| Catalog # | ATGP3540 |
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| Order / More Info | CFB, 26-259aa, Human, His-tag, Baculovirus from ATGen |
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| Product Specific References | n/a |
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