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| Antigenic Specificity | LAP (Latency Associated peptide) |
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| Clone | FNLAP |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1, kappa |
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| Format | phycoerythrin (PE) conjugate |
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| Size | 100 Tests |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 5 µL (0.5 µg)/test |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | LAP (Latency Associated peptide) Monoclonal Antibody (FNLAP), PE, eBioscience™. TGF beta-1 is a polypeptide member of the transforming growth factor beta superfamily of cytokines, found almost ubiquitously in tissues. Transforming growth factor (TGF)-b is stored in the extracellular matrix as a latent complex with its prodomain. Activation of TGF-b1 requires the binding of aV integrin to an RGD sequence in the prodomain and exertion of force on this domain, which is held in the extracellular matrix by latent TGF-b binding proteins. Latent forms are complexes of TGF-beta, an aminoterminal portion of the TGF-beta precursor, designated TGF-LAP (TGF-latency associated peptide), and a specific binding protein, known as LTBP. |
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| Immunogen | n/a |
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| Other Names | CED, DPD1, LAP, TGFB, TGFbeta |
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| Gene, Accession # | Entrez: 7040; Uniprot: P01137 |
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| Catalog # | 12-9829-42 |
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| Order / More Info | LAP (Latency Associated peptide) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 22585562, 26999600, 27525720 |
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