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| Product Name | CSF1, 33-255aa, Human, His-tag, Baculovirus (Bioactivity Validated) |
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| Description | Purity: > 95 % by SDS - PAGE Format: Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol. CSF1, also known as macrophage colony-stimulating factor 1, is a hematopoietic growth factor that is the primary regulator of the survival, proliferation, differentiation and function of mononuclear phagocytes. It is a four alpha-helical bundle cytokine and its active form is found extracellularly as a disulfide linked homodimer. This protein plays important roles in innate immunity, cancer and inflammatory diseases, including systemic lupus erythematosus, arthritis, atherosclerosis and obesity. In several conditions, activation of macrophages involves a CSF1 autocrine loop. In addition, secreted and cell-surface isoforms of CSF1 can have differential effects in inflammation and immunity. Recombinant human CSF1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
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| Size | 50ug, 10ug, |
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| Concentration | n/a |
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| Applications | Bioactivity |
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| Other Names | Macrophage colony-stimulating factor 1, CSF1, M-CSF, MCSF, Lanimostim |
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| Gene, Accession, CAS # | NP 000748 |
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| Catalog # | ATGP3565 |
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| Order / More Info | CSF1, 33-255aa, Human, His-tag, Baculovirus (Bioactivity Validated) from ATGen |
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| Product Specific References | n/a |
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