| 产品详情 |
| Edit |   |
|---|
| Product Name | PIM1, 38-290aa, Human, His tag, E.coli |
|---|
| Description | Purity: > 90% by SDS - PAGE Format: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT . PIM1 belongs to the Ser/Thr protein kinase family, and PIM subfamily. This protein is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AuG (CuG) and downstream AuG codons. Recombinant human Pim1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
|---|
| Size | 250ug, 50ug, 10ug |
|---|
| Concentration | n/a |
|---|
| Applications | SDS-PAGE |
|---|
| Other Names | Non-specific serine/threonine protein kinase, PIM |
|---|
| Gene, Accession, CAS # | NP 002639 |
|---|
| Catalog # | ATGP1997 |
|---|
| Price | |
|---|
| Order / More Info | PIM1, 38-290aa, Human, His tag, E.coli from ATGen |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|