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| Product Name | PRNP, 23-230aa, Human, His tag, E.coli (Denatured) |
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| Description | Purity: > 90% by SDS - PAGE Format: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol. Prion protein, also known as PRNP, is a ubiquitous membrane glycoprotein whose abnormal self-replicating, misfolded form is widely believed to cause several central nervous system disorders, collectively known as Transmissible Spongiform Encephalopathies (TSE). This protein contains a highly unstable region of five tandem octapeptide repeat. Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease, fatal familial insomnia, Gerstmann-Straussler disease, Huntington disease-like 1, and kuru. Recombinant human PRNP protein, fused to His-tag at N-terminus, was expressed in E.coli. |
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| Size | 100ug, 20ug, 4ug |
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| Concentration | n/a |
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| Applications | SDS-PAGE |
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| Other Names | Prion protein preproprotein, Prion protein preproprotein, ASCR, CD230, CJD, GSS, MGC26679, prion, PRIP, PrP, PrP27-30, PrP33-35C, PrPc |
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| Gene, Accession, CAS # | AAH12844 |
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| Catalog # | ATGP2013 |
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| Order / More Info | PRNP, 23-230aa, Human, His tag, E.coli (Denatured) from ATGen |
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| Product Specific References | n/a |
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