| 产品详情 |
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| Antigenic Specificity | CD172a |
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| Clone | OX-41 |
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| Host Species | Mouse |
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| Reactive Species | rat |
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| Isotype | IgG2a, κ |
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| Format | purified |
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| Size | 500 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC), IHC, IP, Western Blot (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Purified anti-rat CD172a (SIRPα). Rat CD172a, also known as a signal-regulatory protein α (SIRPα), is a 75-110 kD transmembrane glycoprotein involved in the receptor tyrosine kinase coupled signaling pathway. It belongs to the Ig superfamily primarily expressed on monocytes/macrophages, granulocytes, dendritic cells and neurons. CD172a serves as a substrate of activated receptor ttyrosine kinases (RTKs). The interaction of the CD172a intracellular domain with SHP-1 and SHP-2 displays negative signaling in the regulation of leukocyte adhesion and transmigration, T cell activation, macrophage fusion and phagocytosis. CD47 (IAP) is an extracellular ligand for CD172a. |
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| Immunogen | Rat peritoneal macrophages |
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| Other Names | SIRPa, PTPNS1, BIT, MFR, p84, CD172 antigen-like family member A |
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| Gene, Accession # | Gene ID: 19261 |
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| Catalog # | 204702 |
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| Price | |
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| Order / More Info | CD172a Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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