| 产品详情 |
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| Antigenic Specificity | LAP |
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| Clone | TW7-28G11 |
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| Host Species | Mouse |
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| Reactive Species | mouse, human |
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| Isotype | IgG2b, κ |
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| Format | purified, azide-free |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC), Western Blot (WB), IP, Neut |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Ultra-LEAF™ Purified anti-mouse/human LAP (TGF-β1). Transforming growth factor beta (TGF-β) is a cytokine that has critical functions in the immune response by regulating Treg and Th17 cell differentiation. TGF-β is first synthesized as pro-TGF-β which is then cleaved by furin proprotein convertase in the Golgi apparatus to produce a latent TGF-β complex. This complex consists of non-covalently associated dimers of the N-terminal region of pro-TGF-β (latency-associated peptide, LAP) and C-terminal region of pro-TGF-β (mature TGF-β). The latent-TGF-β has been found on the membrane of activated Treg cells, immature dendritic cells, megakaryocytes, and platelets. |
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| Immunogen | Mouse Tgfb1-transduced P3U1 cells |
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| Other Names | TGFB, TGFB1, DPD1, Latency Associated Peptide (LAP), TGF-beta1, TGF-beta |
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| Gene, Accession # | Gene ID: 21803 |
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| Catalog # | 146704 |
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| Price | |
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| Order / More Info | LAP Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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| 产品资料 |
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