| 产品详情 |
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| Product Name | Stattic |
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| Description | Stattic is a small molecule that selectively inhibits STAT3 activation, dimerization, and nuclear translocation by preventing the binding of tyrosine-phosphorylated peptide motifs to the STAT3 SH2 domain (IC50 = 5.1 µM at 37°C). Displays selectivity over STAT1, STAT5, c-Myc/Max, Jun/Jun and Lck. At 10 µM, stattic induces apoptosis in STAT3-dependent breast cancer (MDA-MB-231 and MDA-MB-435S) cell lines. MW: 211.19. Purity >98% |
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| Size | 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 6-?Nitro-?1,?1-?dioxide-?benzo[b]thiophene; Stat3 Inhibitor V |
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| Gene, Accession, CAS # | CAS: 19983-44-9 |
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| Catalog # | 2625-25 |
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| Price | |
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| Order / More Info | Stattic from BIOVISION, INC. |
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| Product Specific References | n/a |
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