| 产品详情 |
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| Antigenic Specificity | Bcl-6 |
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| Clone | IG191E/A8 |
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| Host Species | Mouse |
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| Reactive Species | mouse, human |
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| Isotype | IgG1 |
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| Format | Alexa Fluor® 647 conjugate |
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| Size | 25 tests |
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| Concentration | n/a |
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| Applications | Intracellular Staining for Flow Cytometry (ICFC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Alexa Fluor® 647 anti-mouse/human Bcl-6. B-cell lymphoma 6 (Bcl-6), is an 80 kD homodimer and member of the BTB-POZ zinc finger family. It consists of one BTB (POZ) domain and six C2H2-type zinc fingers. Bcl-6 is a transcriptional repressor as well as a master regulator of germinal center reaction. On B cells, Bcl-6 induces proliferation, antibody class switching and affinity maturation, while inhibits its differentiation to plasma cells. On T cells, Bcl-6 induces its differentiation to TFH. This molecule is also expressed in some B cell lymphomas and breast cancer cells. |
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| Immunogen | Plasmid vector containing cDNA of the Bcl-6 gene |
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| Other Names | B-cell lymphoma 6, BCL-5, LAZ3, BCL6A, ZNF51, ZBTB27 |
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| Gene, Accession # | Gene ID: 604, 12053 |
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| Catalog # | 648305 |
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| Price | |
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| Order / More Info | Bcl-6 Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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| 产品资料 |
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