| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | SHMT2 |
|---|
| Clone | OTI3E9 |
|---|
| Host Species | Mouse |
|---|
| Reactive Species | human |
|---|
| Isotype | IgG1 |
|---|
| Format | purified |
|---|
| Size | 100 µl |
|---|
| Concentration | n/a |
|---|
| Applications | Immunohistochemistry (Paraffin): 1:150, Western Blot: 1:2000 |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | SHMT2 Monoclonal Antibody (OTI3E9). Mammalian serine hydroxymethyltransferase (SHMT) is a tetrameric, pyridoxal phosphate (PLP)-dependent enzyme that catalyzes the reversible interconversion of serine and tetrahydrofolate to glycine and methylenetetrahydrofolate in the cytoplasm (cSHMT, SHMT1) and mitochondria (mSHMT, SHMT2). cSHMT preferentially supplies one-carbon units for thymidylate biosynthesis, depletes methylenetetrahydrofolate pools for S-adenosylmethionine (SAM) synthesis by synthesizing serine, sequesters 5-methyltetrahydrofolate, and inhibits SAM synthesis. |
|---|
| Immunogen | n/a |
|---|
| Other Names | GLYA, SHMT, GLY A+, glycine auxotroph A, human complement for hamster, glycine hydroxymethyltransferase, serine aldolase, serine hydroxymethylase, serine hydroxymethyltransferase, mitochondrial, serine methylase, threonine aldolase |
|---|
| Gene, Accession # | Entrez: 6472; Uniprot: P34897 |
|---|
| Catalog # | MA5-27058 |
|---|
| Price | |
|---|
| Order / More Info | SHMT2 Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|