| 产品详情 |
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| Antigenic Specificity | CD49e |
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| Clone | NKI-SAM-1 |
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| Host Species | Mouse |
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| Reactive Species | human, African green, baboon, cynomolgus, rhesus |
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| Isotype | IgG2b, κ |
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| Format | allophycocyanin (APC) conjugate |
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| Size | 100 tests |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | APC anti-human CD49e. CD49e is a type I integral membrane glycoprotein, known as α5 integrin, VLA-5 α chain. It forms noncovalent heterodimer with integrin β1 (CD29). CD49e contains two disulfide-linked subunits of 135 kD and 24 kD, and is mainly expressed on thymocytes, activated lymphocytes, endothelial cells, osteoblasts, melanoma, and some myeloid leukemia cells. CD49e/CD29 complex binds to fibronection and neural adhesion molecule L1. It mediates monocytes migration, involves in the regulation of cells survival and apoptosis, and co-stimulates T cell activation. |
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| Immunogen | U937 cells |
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| Other Names | α5 integrin, VLA-5 α chain, Integrin α5 |
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| Gene, Accession # | Gene ID: 3678 |
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| Catalog # | 328012 |
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| Price | |
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| Order / More Info | CD49e Antibody from BIOLEGEND |
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| Product Specific References | PubMed: 24623721 |
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| 产品资料 |
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