| 产品详情 |
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| Antigenic Specificity | Cbl |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 125 µl |
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| Concentration | n/a |
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| Applications | Western Blot (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Purified anti-Cbl. The proto-oncogene c-Cbl was initially identified as the cellular homologue of v-Cbl oncogene that induces pre-B cell lymphomas and myeloid leukemias in mice. The Cbl family comprises three mammalian proteins, c-Cbl, Cbl-b, and Cbl-3; among these, c-Cbl and Cbl-b are expressed in hemopoietic cells, whereas Cbl-3 is expressed only in epithelial tissues. Cbl proteins can function as E3 ubiquitin (Ub) ligases, and in more recent studies Cbl has been implicated in the negative regulation of various RTKs. |
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| Immunogen | peptide mapping to the carboxy terminal domain of human Cbl |
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| Other Names | E3 ubiquitin-protein ligase Cbl, Proto-oncogene c-Cbl |
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| Gene, Accession # | Gene ID: 867 |
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| Catalog # | 633001 |
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| Price | |
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| Order / More Info | Cbl Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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