产品详情 |
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Antigenic Specificity | GLRB |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | purified |
Size | 50 µl |
Concentration | lyophilized |
Applications | Western Blot: 1:200-1:1000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | GLRB Polyclonal Antibody. In the central nervous system (CNS), glycine-mediated inhibitory neurotransmission is essential to voluntary motor control and reflex responses. Glycine binds to glycine receptors (GlyR) in the postsynaptic neuronal membranes. GlyR, gamma-aminobutryic acid, serotonin and acetylcholine comprise an evolutionally conserved superfamily of ligand-gated ion channels. The pentameric subunit structure of GlyR consists of two types of glycosylated membrane proteins, α1 through α4 and β, and an associated peripheral membrane protein, which combine to form a chloride-selective ion channel. In humans, the composition of the pentamer changes from α2 subunits in the fetal CNS to alpha1 and beta subunits in |
Immunogen | n/a |
Other Names | Glycine Receptor beta |
Gene, Accession # | Entrez: 14658, 25456, 2743; Uniprot: P20781, P48167, P48168 |
Catalog # | PA5-77443 |
Price | |
Order / More Info | GLRB Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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