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| Product Name | AZ 10606120 dihydrochloride |
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| Description | Potent P2X7 receptor antagonist (KD values are 1.4 and 19 nM at human and rat P2X7 receptors respectively). Binds in a positive cooperative manner to sites distinct from, but coupled to, the ATP binding site and acts as a negative allosteric modulator. Inhibits tumor growth and displays antiangiogenic effects in mice. Purity 98%. MW (observed): 495.48 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-[2-[[2-[(2-Hydroxyethyl)amino]ethyl]amino]-5-quinolinyl]-2-tricyclo[3.3.1.13,7]dec-1-ylacetamide dihydrochloride |
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| Gene, Accession, CAS # | CAS: 607378-18-7 |
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| Catalog # | 3323/10 |
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| Order / More Info | AZ 10606120 dihydrochloride from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 21542899, 22394324, 22506590, 22661222, 24163006, 24671093, 24970925, 25266676, 25752193, 26050734, 26607222, 26877061, 27385778, 28389651 |
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