| 产品详情 |
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| Antigenic Specificity | IL-16 |
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| Clone | 14.1 |
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| Host Species | Mouse |
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| Reactive Species | human, cross-reactivity: mouse |
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| Isotype | IgG2a |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Intracellular Staining for Flow Cytometry (ICFC), ELISA, IHC |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Purified anti-human IL-16. Interleukin-16 is a proinflammatory cytokine synthesized as a 68 kD precursor molecule (pro-IL-16). After cleavage of pro-IL-16 by caspase-3, IL-16 is released as a 12 kD protein, but its biologic activities are exerted by a tetramer. IL-16 is a chemoattractant for CD4+ T cells, monocytes, and eosinophils. On T cells, IL-16 upregulates CD25 and class II expression, and also inhibits HIV-1 replication in vitro by repressing the transcription of the HIV-1 long terminal repeat. IL-16 is expressed by lymphocytes, macrophages, eosinophils, mast cells, epithelial cells, and fibroblasts. CD4 and CD9 are the receptors of IL-16. |
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| Immunogen | Peptide corresponding to amino acids 615 to 630 (RRKSLQSKETTAAGDS) of IL-16 |
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| Other Names | Interleukin-16 |
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| Gene, Accession # | Gene ID: 3603 |
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| Catalog # | 519102 |
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| Price | |
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| Order / More Info | IL-16 Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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| 产品资料 |
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