产品详情 |
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Product Name | MJ15 |
Description | A potent CB1 receptor antagonist (IC50 = 118.9 pM; Ki = 27.2 pM for rat CB1); selective for CB1 over CB2, exhibiting only 46% inhibition of CB2 at a concentration of 10 µM; reverses (+)-WIN 55,212-2 inhibition of forskolin-induced cAMP accumulation in a dose-dependent manner in CHO cells expressing human CB1; reduces food intake and body weight gain in a rat model of diet-induced obesity at a dose of 40 mg/kg; reduces body weight gain and white adipose accumulation in a mouse model of early onset diet-induced obesity |
Size | 25 mg |
Concentration | n/a |
Applications | n/a |
Other Names | MJ-15 CB-1 |
Gene, Accession, CAS # | CAS: 944154-76-1 |
Catalog # | 11956-25 |
Price | |
Order / More Info | MJ15 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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