| 产品详情 |
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| Antigenic Specificity | PACSIN1 |
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| Clone | 10A6B55 |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG2b, κ |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Western Blot (WB), IP |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Purified anti-PACSIN1. PACSIN1, also known as syndapin-1, is a member of the protein kinase C and casein kinase substrate in neurons (PACSIN) family. PACSIN1 was originally identified as a neuron-specific phosphoprotein, interacting with the endocytic regulatory proteins synaptojanin 1, WASP, and dynamin-1 via its highly conserved SH3 domain. PACSIN1 is highly expressed in the brain and expressed at a lower level in the liver, heart, and pancreas. PACSIN1 plays important roles in synaptic vesicle endocytosis and cytoskeletal reorganization. It has also been demonstrated that PACSIN1 regulates the TLR7/9-mediated type I interferon response in plasmacytoid dendritic cells. |
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| Immunogen | Partial mouse PACSIN1 recombinant protein (26-275 a.a.) expressed in E. coli. |
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| Other Names | Protein kinase C and casein kinase substrate in neurons protein 1, Syndapin-1 |
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| Gene, Accession # | Gene ID: 23969 |
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| Catalog # | 660902 |
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| Price | |
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| Order / More Info | PACSIN1 Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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