| 产品详情 |
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| Antigenic Specificity | PADI4 |
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| Clone | O94H5 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse |
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| Isotype | IgG2a |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Western Blot (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Purified anti-PADI4. PADI4 is an enzyme that catalyzes peptidyl arginine to citrulline in the presence of Ca2+ ions. This reaction, known as citrullination, leads to the post-translational modification of proteins. PADI4 was initially cloned from the HL-60 cell line (human promyelocytic leukemia cells). It is mainly expressed in granulocytes, monocytes and CD34+ stem cells. PADI4 may play a role in granulocyte and macrophage development leading to inflammation and immune response. The PADI4 single-nucleotide polymorphism (SNP) and haplotypes were associated with rheumatoid arthritis susceptibility. Recently, PADI4 has also been found in a variety of malignant tumors and implies its potential roles in tumorigenesis. |
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| Immunogen | Full length recombinant protein of human PADI4 expressed in HEK293T. |
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| Other Names | Peptidylarginine deiminase 4, Peptidyl Arginine Deiminase, Type IV, PADI5, HL-60 PAD, Protein-Arginine Deiminase Type-4, PAD4 |
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| Gene, Accession # | Gene ID: 23569 |
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| Catalog # | 684202 |
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| Price | |
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| Order / More Info | PADI4 Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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