产品详情 |
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Product Name | Pioglitazone |
Description | A PPARγ agonist (EC50 = ~500-600 nM for both human and murine PPARγ); selective for PPARγ over PPARα exhibiting low level activation of PPARα at 1 µM and 5.4-fold activation at a concentration of 10 µM; reduces hyperglycemia, hyperlipidemia, and hyperinsulinemia in a dose-dependent manner in male Wistar fatty rats from 0.3-3 mg/kg; reduces the number of lesions in a TRAP model; decreases production of neuroinflammatory cytokines and reduces immobility in the forced swim and tail suspension tests in a mouse model of chronic mild stress at 2.5 mg/kg |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | U-72107 |
Gene, Accession, CAS # | CAS: 111025-46-8 |
Catalog # | 71745-5 |
Price | |
Order / More Info | Pioglitazone from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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