| 产品详情 |
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| Antigenic Specificity | Notch 2 |
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| Clone | MHN2-25 |
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| Host Species | Mouse |
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| Reactive Species | human, African green |
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| Isotype | IgG2a, κ |
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| Format | purified |
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| Size | 25 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Purified anti-human Notch 2. The Notch receptors are a type I transmembrane protein family that share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. They are highly conserved from invertebrates to mammals. Notch 1 and Notch 2 exhibit the highest structural similarity among the four mammalian Notch receptors (Notch1-4). Notch1 and Notch 2 are reported to be functionally redundant. Notch 2 is expressed by Pre-B cells, double negative and CD8 single positive thymocytes, brain, lung cells. Notch 2 functions as a receptor for Jagged and Delta ligands, and may play a role in vascular, renal and hepatic development. |
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| Immunogen | Human Notch 2-human IgG1 Fc fusion protein |
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| Other Names | Neurogenic locus notch homolog protein 2, hN2, fN2 |
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| Gene, Accession # | Gene ID: 4853 |
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| Catalog # | 348301 |
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| Price | |
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| Order / More Info | Notch 2 Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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| 产品资料 |
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