| 产品详情 |
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| Antigenic Specificity | p63 (DN) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 50 µl |
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| Concentration | n/a |
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| Applications | Western Blot (WB), IHC |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Purified anti-p63 (ΔN). Reactivity: Human (recognizes δN-isoforms). p63 (ΔN) is a member of the p53 family. This protein has multiple isoforms TA p63-α, -β, γ, ΔN p63-α, -β, and -γ. The molecular weights of the p63 isoforms α=66 kD, β=52 kD, and γ=45 kD. This nuclear protein is essential for limb formation, epidermal morphogenesis, and epithelial stem cell regeneration. ΔN isoforms are antagonistic to p53; TA isoforms can transactivate p53 targets. The p63 ΔN isoforms repress TA isoforms; mutant p53 abrogates p63 transactivation. This protein interacts with p53, p73, and the various TA- and ΔN isoforms. The Poly6190 antibody recognizes human p63 ΔN isoforms and has been shown to be useful for Western blotting. |
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| Immunogen | Modified peptide |
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| Other Names | p63, Isoforms TA p63-α, -β, -γ, ΔN p63-α, -β, -γ |
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| Gene, Accession # | Gene ID: 8626 |
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| Catalog # | 619001 |
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| Price | |
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| Order / More Info | p63 (DN) Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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| 产品资料 |
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