| 产品详情 |
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| Antigenic Specificity | CD11b (activated) |
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| Clone | CBRM1/5 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1, κ |
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| Format | purified, azide-free |
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| Size | 50 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC), IP, Block |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | LEAF™ Purified anti-human CD11b (activated). The CBRM1/5 antibody reacts with an activated form of human CD11b, a 165-170 kD type I transmembrane glycoprotein also known as αM integrin, Mac-1, CR3, and C3biR. CD11b non-covalently associates with integrin β2 (CD18) and is expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b/CD18 is critical for the transendothelial migration of monocytes and neutrophils as well as adhesion, phagocytosis, and neutrophil activation. CD11b/CD18 interacts with ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4, CD14, CD23, heparin, iC3b, fibrinogen and factor X. |
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| Immunogen | n/a |
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| Other Names | Integrin αM chain, C3biR, CR3, Mac-1, Mo1, αM Integrin |
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| Gene, Accession # | Gene ID: 3684 |
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| Catalog # | 301407 |
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| Price | |
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| Order / More Info | CD11b (activated) Antibody from BIOLEGEND |
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| Product Specific References | PubMed: 16601240,16751380,20400675,21098104,22474248,23077025,23999103,24989774 |
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