| 产品详情 |
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| Antigenic Specificity | CD268 (BAFF-R, BAFFR) |
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| Clone | 11C1 |
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| Host Species | Mouse |
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| Reactive Species | human, African green, baboon, cynomolgus, rhesus |
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| Isotype | IgG1, κ |
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| Format | allophycocyanin (APC) conjugate |
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| Size | 100 tests |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | APC anti-human CD268 (BAFF-R). B cell-activating factor receptor (BAFF-R) is a 19 kD type III membrane protein. It belongs to TNFR superfamily, also known as TNFRSF member 13C (TNFRSF13C), BAFF receptor 3 (BR3), or CD268. BAFF-R is expressed on mature B cells, B cell lymphoma, and T cell subset. BAFF-R is the major receptor for BAFF/BLys (or TALL-1, THANK) which binds to TACI and BCMA as well. The interaction of BAFF with BAFF-R promotes NF-κB activation and plays predominant roles in B-cell maturation and survival as well as costimulates T cell activation and proliferation. TRAF3 is a BAFF-R intracellularly associated protein, which negatively regulates BAFF-R-mediated NF-κB activation. |
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| Immunogen | BAFF-R-L1.2 transfectants |
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| Other Names | BR3, BLyS Receptor 3, BAFF Receptor |
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| Gene, Accession # | Gene ID: 115650 |
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| Catalog # | 316916 |
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| Price | |
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| Order / More Info | CD268 (BAFF-R, BAFFR) Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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